Bangladesh Prime Minister Sheikh Hasina has resigned and left the country on Monday, media reports said, as more people were killed in some of the worst violence since the birth of the South Asian nation more than five decades ago.

Bangladesh Army Chief Wakar uz Zaman held a press conference and said that the Army would decide the future matters of the country and the Army would hold talks with the political parties to form an interim government in the wake of Sheikh Hasina Wazed's resignation confirmation news.

"There is a crisis in the country. I have met Opposition leaders and we have decided to form an interim government to run this country. I take all responsibility and promise to protect your life and property. Your demands will be fulfilled. Please support us and stop violence. If you work with us, we can move towards a proper solution. We cannot achieve anything through violence," he said.

"She and her sister have left Ganabhaban (the Prime Minister's official residence) for a safer place," the source told AFP.

“She wanted to record a speech. But she could not get an opportunity to do that.”

Bangladesh's army chief Waker-Uz-Zaman said Monday he would "form an interim government" after the prime minister resigned and fled the capital in the face of overwhelming protests.

"I am taking full responsibility," the general said, dressed in military fatigues and cap, although it was not immediatly clear if he would head a caretaker government.

"We will form an interim government," Waker said in a broadcast to the nation on state television, adding that Sheikh Hasina had resigned.

"The country has suffered a lot, the economy has been hit, many people have been killed -- it is time to stop the violence," he added.

"I hope after my speech, the situation will improve."

He said he would talk to the president to form the interim government and had held talks with the main opposition parties and civil society members -- but not Hasina's Awami League.

Waker is a career infantry officer who has spent nearly four decades in the military, serving two tours as a UN peacekeeper as well as in the prime minister's office.

"If the situation gets better, there is no need for emergency", he said, vowing the new authorities would "prosecute all murders" following weeks of deadly protests.

"Now the task of the students is to keep calm and help us," he said.

Bedecked with medal ribbons on his green uniform, the mild-looking and spectacle-wearing officer was appointed to the military's top job as chief of army staff earlier this year.

Earlier, Bangladesh Prime Minister Sheikh Hasina's resignation is a "possibility", French news agency AFP reported on Monday, as six more people were killed in some of the worst violence since the birth of the South Asian nation more than five decades ago.

Hasina's resignation is a "possibility", AFP reported citing a senior aide. Reuters could not immediately verify the report. Hasina and her sister had been taken to a "safe shelter" away from her official residence, a government source told Reuters.

"You see, the situation is very volatile. What is happening, I myself don’t know," Law Minister Anisul Huq told Reuters.

Student activists had called for a march to the capital Dhaka on Monday in defiance of a nationwide curfew to press Hasina to resign, a day after deadly clashes across the country killed nearly 100 people.

As protesters began to march in some places, armoured personnel carriers and troops patrolled the streets of the capital, Reuters TV showed. There was little civilian traffic, barring a few motorcycles and three-wheel taxis.

Must Read:

Bangladesh election: Hasina set for 5th term amid boycott, crackdown

Bangladesh PM Sheikh Hasina presents souvenir to this Pakistani diplomat

Look back at Bangladesh's 50-year election history, as it heads to polls tomorrow

At least six people were killed in clashes between police and protesters in the Jatrabari and Dhaka Medical College areas on Monday, the Daily Star newspaper reported. Reuters could not immediately verify the report.

Police hurled sound grenades in some parts of the city to disperse small groups of protesters, the Bengali language Prothom Alo newspaper reported.

Elsewhere, thousands of protesters had surrounded law enforcement officers stationed in front of a key building, it said.

Army chief General Waker-Uz-Zaman, who was due to address the nation at 2 p.m. local time (0800 GMT) would now do so at 3 p.m. (0900 GMT), an army officer told Reuters. "He is holding talks with some stakeholders, outside the military. That’s why the delay," the officer said.

The military spokesperson's office had earlier said that "the public is requested to refrain from violence and be patient," until the army chief's address, Prothom Alo reported.

Bangladesh has been engulfed by protests and violence that began last month after student groups demanded scrapping of a controversial quota system in government jobs.

That escalated into a campaign to seek the ouster of Hasina, who won a fourth straight term in January in an election boycotted by the opposition.

At least 91 people were killed and hundreds injured on Sunday in a wave of violence across the country of 170 million people as police fired tear gas and rubber bullets to disperse tens of thousands of protesters.

Starting Sunday evening, a nationwide curfew has been imposed, the railways have suspended services and the country's huge garments industry has closed.