A tragic crash involving a small Learjet 55 aircraft occurred on Friday evening in Northeast Philadelphia, causing multiple fatalities and widespread destruction.

The plane, a medical evacuation air ambulance, crashed shortly after departing from Northeast Philadelphia Airport, reportedly killing all six people on board. The victims included four crew members, a pediatric medical patient, and the patient's escort.

The aircraft was en route to Springfield-Branson National Airport in Missouri when it crashed, bursting into flames and setting several nearby homes on fire. Local authorities have confirmed that at least one house and multiple vehicles were consumed by the fire, while visibility was significantly reduced due to rain at the time of the incident.

Philadelphia's emergency management office responded swiftly, labelling the crash a "major incident" and confirming road closures in the vicinity.

The crash site, located just under five kilometers from the airport, has been described as chaotic, with emergency responders working tirelessly to manage the crisis.

Secretary of Transportation Sean Duffy confirmed the number of people on board as six, while noting that both the Federal Aviation Administration (FAA) and the National Transportation Safety Board (NTSB) would conduct a joint investigation into the cause of the crash.

In a statement, Jet Rescue Air Ambulance, the company operating the aircraft, expressed sorrow over the tragedy, stating that it was unable to confirm any survivors. As the incident unfolded, Philadelphia Mayor Cherelle Parker assured the public that authorities were doing everything possible to assess the situation, though she could not provide any details on the exact number of casualties.

The crash came just days after a devastating mid-air collision between a US Army Black Hawk helicopter and a passenger plane near Washington D.C., which resulted in the deaths of 67 people.

President Donald Trump, in a post on Truth Social, expressed his condolences, stating, "So sad to see the plane go down in Philadelphia, Pennsylvania. More innocent souls lost. Our people are totally engaged. First responders are already being given credit for doing a great job. More to follow. God Bless you all."